The structure of ipomoeassin F-bound Sec61alpha has been solved, https://www.biorxiv.org/content/10.1101/2022.08.11.503542v1.full
https://www.biorxiv.org/content/10.1101/2022.08.11.503542v1.full
https://www.biorxiv.org/content/10.1101/2022.08.11.503542v1.full
Seth is currently an undergraduate student majoring in Exercise Science at Ball State. He will be helping with chemical synthesis of various open-chain analogues and probes to explore biology for drug discovery.
Dillon is currently an undergraduate student majoring in Biology at Ball State. He will be helping with setup of our in-house protocols for cell culture and cytotoxicity assays while receiving training in organic synthesis.
Griffin is currently an undergraduate student majoring in Biology at Ball State. He will be helping with setup of our in-house protocols for cell culture and cytotoxicity assays while receiving training in organic synthesis.
Courtney is currently an undergraduate student majoring in Biology at Ball State. She will be helping with setup of our in-house protocols for cell culture and cytotoxicity assays.
Katie is currently a sophomore undergraduate student majoring in Chemistry at Ball State. This is her first academic research experience. Together with other undergraduate students, she will be working on efficient preparation of glucose trichloroacetimidate donors that can be utilized as general synthetic building blocks for many natural and synthetic target molecules.
On June 16, Kwabena successfully defended his master thesis research on developing an efficient synthesis of a glucose trichloroacetimidate donor, which requires only a single column over seven steps. The overall yield for the synthesis is ~46%, which accounts for ~90% for each step. His methodology highlights a novel protocol for a key NBS-mediated desulfuration […]